Polycystic Ovary Syndrome (PCOS) is a common hormonal disorder in women of reproductive age, affecting approximately 1 in 10 women worldwide. One of the main symptoms of PCOS is difficulty getting pregnant due to irregular ovulation and hormone imbalances. As a result, many women with PCOS turn to fertility supplements as a natural way to improve their chances of conceiving. However, with so many supplements on the market claiming to boost fertility, it can be overwhelming and confusing to know which ones actually work and which ones are just a waste of money. In this blog post, we will discuss the top fertility supplements for PCOS and separate fact from fiction to help you make informed decisions about your fertility journey.
First, let’s understand how PCOS affects fertility. PCOS is characterized by high levels of male hormones (androgens), irregular periods, and enlarged ovaries with multiple small cysts. These imbalances can interfere with the normal ovulation process and make it difficult to get pregnant. Additionally, women with PCOS often have insulin resistance, which can lead to weight gain and further hormonal imbalances. Therefore, the goal of fertility supplements for PCOS is to regulate hormones, improve ovulation, and address underlying insulin resistance.
The most commonly recommended fertility supplements for PCOS include inositol, vitamin D, and omega-3 fatty acids. Inositol, a type of B vitamin, has been shown to improve ovulation and insulin sensitivity in women with PCOS. A study published in the European Review for Medical and Pharmacological Sciences found that women who took a combination of myo-inositol and D-chiro-inositol had a higher rate of ovulation and pregnancy compared to those who took a placebo. In addition, inositol has been shown to reduce symptoms of androgen excess, such as acne and excess hair growth.
Vitamin D deficiency is common in women with PCOS and can contribute to hormonal imbalances and menstrual irregularities. A study published in the International Journal of Endocrinology found that vitamin D supplementation improved menstrual regularity and increased the chances of pregnancy in women with PCOS. It is recommended to have your vitamin D levels checked and supplement if necessary, as deficiency is prevalent among women with PCOS.
Omega-3 fatty acids, specifically the types found in fish oil, have been shown to have beneficial effects on fertility in women with PCOS. A study published in the Journal of Clinical Endocrinology and Metabolism found that women with PCOS who took a daily supplement of 4 grams of fish oil had improved ovulation and pregnancy rates. Omega-3 fatty acids have anti-inflammatory properties, which can help reduce insulin resistance and regulate hormones in women with PCOS.
Another popular fertility supplement for PCOS is a combination of myo-inositol and N-acetylcysteine (NAC). NAC is a precursor to glutathione, a powerful antioxidant that helps reduce oxidative stress in the body. A study published in the Journal of Ovarian Research found that women with PCOS who took a combination of myo-inositol and NAC had improved ovulation and pregnancy rates compared to those who took a placebo. Additionally, the combination of these two supplements has been shown to improve insulin sensitivity and reduce hirsutism (excess hair growth).

Fertility Supplements and PCOS: What Works and What Doesn't
While these supplements have shown promising results for women with PCOS, it is important to note that they should not be used as a standalone treatment. It is crucial to also make lifestyle changes, such as maintaining a healthy weight, managing stress, and following a balanced diet, to improve fertility outcomes. Additionally, it is recommended to consult with a healthcare professional before starting any new supplement regimen, especially if you are taking other medications or have underlying health conditions.
Now, let’s discuss some fertility supplements that have not been proven to be effective for women with PCOS. One of these supplements is vitex (chasteberry), which is often marketed as a natural treatment for hormonal imbalances and infertility. However, a study published in the Journal of Human Reproductive Sciences found that vitex was no more effective than a placebo in improving fertility outcomes in women with PCOS. In fact, it may even worsen symptoms such as acne and hair loss in some women.
Another supplement that has gained popularity for PCOS is maca root. Maca is a plant native to Peru and is believed to have hormone-balancing properties. However, there is limited research on its effectiveness for PCOS-related infertility. A study published in the journal Andrologia found that maca had no significant effect on ovulation or hormone levels in women with PCOS. More research is needed to determine the true benefits of maca for PCOS and fertility.
In addition to taking supplements, it is important for women with PCOS to work with a healthcare professional to monitor hormone levels and make necessary adjustments to their treatment plan. It may also be helpful to track ovulation using methods such as tracking basal body temperature or using ovulation predictor kits.
In conclusion, while there is no magic pill for improving fertility in women with PCOS, certain supplements can be beneficial when used in conjunction with lifestyle changes and medical treatment. Inositol, vitamin D, omega-3 fatty acids, and a combination of myo-inositol and NAC have shown promising results in improving ovulation and pregnancy rates in women with PCOS. On the other hand, supplements such as vitex and maca have not been proven to be effective for PCOS-related infertility. It is important to consult with a healthcare professional before starting any new supplement regimen and to remember that supplements should not be used as a substitute for medical treatment.
In summary, fertility supplements can be a useful addition to the treatment plan for women with PCOS, but they should not be relied upon as the sole solution. Inositol, vitamin D, omega-3 fatty acids, and a combination of myo-inositol and NAC have shown promising results in improving fertility outcomes in women with PCOS. However, supplements such as vitex and maca have not been proven effective and may even worsen symptoms in some cases. It is important to consult with a healthcare professional and make necessary lifestyle changes to improve fertility outcomes in women with PCOS.

